Name: Nolvadex (Tamoxifen)
Spec: 10mg*60 tablets/box
MIN Order: 1 box
Tamoxifen (Nolvadex) is an antiestrogen. Nolvadex treats breast cancer that has spread to other sites in the body. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation) to decrease the risk of developing breast cancer. It is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, hence tamoxifen may be characterized as a mixed agonist/antagonist. It has been the standard endocrine (anti-estrogen) therapy for hormone receptor-positive early breast cancer in pre-menopausal women, although aromatase inhibitors have been proposed.
Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
Tamoxifen was discovered by ICI Pharmaceuticals (now AstraZeneca) and is sold under the trade names Nolvadex, Istubal, and Valodex. However, the drug, even before its patent expiration, was and still is widely referred to by its generic name "tamoxifen."
Delivery and shipping:
1.We will send the products within 1 day after your payment is received.
2.We will send the products by DHL,EMS or other shipping methods. As soon as we send out, we will email you tracking No.!
3.Usually you can get the products within 5-7days. If the goods are lost or not been received for other reasons, we'll resend.
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